Combine the cantaloupe with the honey, lime juice, water, and pinch of salt in a blender.
Cover and blend on high until the mixture is very smooth.
Use a spoon to remove any foam that has formed on top while blending and discard it.
Serve the cantaloupe agua fresca immediately over ice or chill for up to 3 days. Right before serving, shake or stir to combine the ingredients because they will separate.